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: Tập 30, số 2A/2024     : 253-260
Publishing year: 7/2024
In this work, poly(vinylpyrrolidone) coated MnO nanoparticles (MnO@PVP NPs) were prepared by the polyol method using triethylene glycol (TEG) and poly(vinylpyrrolidone) (PVP) as solvents and surfactants. The materials' structure, morphology and characteristic properties were analyzed using XRD, TEM, FTIR and DLS measurements. MnO nanoparticles synthesized under optimized conditions have a spherical shape with an average size of 10.87 ± 1.19 nm, demonstrating good image contrast signal enhancement in magnetic resonance imaging (MRI) diagnostic techniques. Research results show that nano MnO@PVP NPs have a high value of longitudinal relaxivities r1 (5.28 mM-1s-1), reducing longitudinal relaxation times T1 and thus increasing MRI signal intensity. The research results show that PVP-coated MnO nanoparticles can be used as T1 positive contrast agents for diagnostic imaging applications shortly.