Bài báo khoa học

The essential oils from the leaves and rhizomes of M. cristatissima displayed moderate antimicrobial activity (Table 2). The essential oil from the leaves of M. cristatissima was the most active against Enterococcus faecalis ATCC299212, Bacillus cereus ATCC14579 and Candida albicans ATCC 10231, with minimum inhibitory concentration (MIC) values of 64.0 μg/mL. The obtained IC50 values were 20.45, 29.45, and 18.45 μg/mL, respectively. The rhizome essential oil displayed lower antimicrobial activity against the microorganism mentioned previously, with MIC values of 128.0, 256.0, and 256.0 μg/mL, respectively, and IC50 values of 39.45, 98.67, and 102.56 μg/mL, respectively. Both essential oils exhibited similar activity towards Staphylococcus aureus ATCC25923 (MIC = 128.0 μg/mL). In addition, both the leaf and rhizome oils exhibited no antimicrobial activity against Gram-negative microorganisms of Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC27853, and Salmonella enterica ATCC13076. Overall, the studied essential oils exhibited moderate antimicrobial activity against the tested microorganisms. This shows that Amomum essential oils selectively inhibit the growth of different microorganisms. The chemical constituents and antimicrobial activity of M. cristatissima essential oils are being reported for the first time. It is believed that the constituents present in the studied essential oils might have influenced the observed antimicrobial activity of M. cristatissima. A section of the chemical compounds identified in the essential oils were reported previously, to possess antimicrobial activity, including α-pinene [12], β-pinene [12], bornyl acetate [12], camphene [13] caryophyllene oxide [14], (E)-nerolidol [14], and spathulenol [14]