Bài báo khoa học

This study highlighted the ability of strain MP1 to degrade cellulose and hemicellulose and produce levan. Out of 65 isolated termite gut symbiotic bacteria, isolate MP1, identified as C. cellulans, exhibited the highest specific cellulase activity. The genome of C. cellulans MP1 is one of 17 genomes of C. cellulans that are released onto the NCBI genome database, but it is the first sequence that has been reported in detail from a biotechnological perspective. Both genomic and experimental evidence proved that C. cellulans MP1 possesses 30 cellulose and 21 hemicellulose-related sequences, which were functionally redundant for endoglucanases, endoxylanase, β-glucosidases, xylanase, β-xylosidases, arabinofuranosidase, and pectate lyase. Moreover, sacC1-levB-sacC2-ls operon involved in levan and L-FOs production was pronounced for the first time, which could be a selective advantage during host-adaptation and colonization. These findings not only enrich the genome database but also provide a valuable source of information to continue research into the potential applications of C. cellulans MP1, including its possible use in the biofuel, pulp and paper, and pharmaceutical industries.