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Chemical constituents from the fruiting bodies of Daldinia concentrica (Bolton fr. ces. & De not) and their anti-inflammatory activity
Authors: Hoang Van Trung, Ping-Chung Kuo, Nguyen Ngoc Tuan, Nguyen Thi Ngan, Nguyen Tan Thanh, Tian-Shung Wu, Tran Dinh Thang
283    0
Nat Prod.Com. Research
:     :
: DOI: 10.1177/1934578X1984632
Publishing year: 5/2019
One new cytochalasin daldinin (1), 2 known cytochalasins 2 and 3, along with 2 steroids 4 and 5, were characterized from the methanol extracts of the fruiting bodies of Daldinia concentrica. The structure of new compound 1 was elucidated using a combination of 1- and 2-dimensional nuclear magnetic resonance spectroscopic and high-resolution electrospray ionization mass spectrometric analyses. In addition, the isolated compounds were examined for their cytotoxicity against several tumor cell lines and the tested compounds demonstrated moderate-to-weak cytotoxicity.
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