Transformation Chlorophyll a of Spirulina platensis to Chlorin e6 Derivatives and Several Applications
Authors: Hai Minh Le
Open Access Macedonian Journal of Medical Sciences
: 2019 Dec 30; 7(24) : 6
Publishing year: 12/2019
Abstract
BACKGROUND: Spirulina platensis contains a large amount of chlorophylls, chlorophyll a, that are starting materials to synthesize functionalized chlorins. Chlorin e6 (Ce6) as well as its derivatives are second generation sensitizers using in photodynamic therapy (PDT) of various cancers. In this study, we transfer chlorophyll a of S. platensis to Ce6derivatives and determine their several applications.
AIM: to evaluate the effects of Ce6 derivatives to treat cancer cells.