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Optimization of total phenolic and total flavonoid extraction conditions from leaves of launaea sarmentosa using the response surface methodology
Authors: Nguyen Tan Thanh, Tran Dinh Thang, Nguyen Thi Huyen, Tran Thi Thu Ha
398    3
Tạp chí Phân tích Hóa, Lý và Sinh học
: 25/2     : 214-220
: 1213-28-.pdf
Publishing year: 10/2020
The Central composite design (CCD) of response surface methodology (RSM) was used to investigate the effects of three factor as extraction temperature (°C), extraction time (min) and ethanol concentration (%) of Launaea sarmentosa leaves on the responses: total phenolic content (TPC) and total flavonoid content (TFC). The optimal conditions obtained from response RSM were 90% v/v for the solvent ratio, 54°C for extraction temperature and 110min for extraction time. The experimental values of TPC and TFC were 318.85±0.32 mgGAE/g, 8.21±0.14 mgCE/g.
Launaea sarmentosa, total phenolic content (TPC), total flavonoid content (TFC), response surface methodology (RSM), extraction.
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